WO2012068343 QUINOLINE DERIVATIVES AS PIK3 INHIBITORS

Effects on PI3KAKTmTOR Signaling and Sensitivity to PIK3 Inhibitors pik3 Reaction PIK3 in Recon3D Phosphatidylinositol 3-kinase pik3 We analyzed 479 patients with NSCLC who underwent NGS and 61 patients were identified with alteration in PIK3 pathway (tissue NGS in 43 and blood-based

pik3 GSK2636771 is a p110β isoform-specific inhibitor of PIK3 with SF50 more than 1 μM PI3K has 4 catalytic subunits: p110α,